Pregnenolone: What Is It and Why Is It Different

taking pregnenolone

Pregnenolone is a steroid hormone that is naturally synthesized in the body. Pregnenolone is responsible for aiding the body to produce other steroid hormones, including progesterone, estrogen, and DHEA. Although taking pregnenolone is naturally synthesized by the body, many people still consume pills and supplements that contain the substance as it is said to enhance memory sharpness. 

There are many benefits of taking pregnenolone, including fighting specific ailments such as Alzheimer’s disease, arthritis, endometriosis, fibrocystic breast condition, and multiple sclerosis scleroderma, premenstrual syndrome, psoriasis, and lots more. Pregnenolone is also said to be an anti-depressant. It is generally used to sharpen memory, prevent fatigue, reduces stress, prevents heart diseases, stimulate the immune system, promote body detoxification, lessens stress, and slow down the rate of aging. As is common with the intake of supplements, there are possible side effects of consuming the substance, some of which are insomnia, mood swings, restlessness and anxiety, irregular heart rhythm, headaches, alopecia, and excessive growth of facial hairs, amongst many others. 

It is essential to consult a health care provider before consuming any substance or supplements containing prednisolone because there is very little knowledge about the substance and its effects on the body. It is also very vital to stick to your doctor or health care provider’s prescription when consuming the substance. 

Why is Pregnenolone Different from Other Steroid Hormones in The Body? 

The presence of hormones controls our body function; thus, there are many different hormones for different body functions. Pregnenolone is one of the steroid hormones in the body alongside DHEA hormone. It’s easy to confuse both hormones because they are both steroid hormones; however, the question is: “is pregnenolone the same as DHEA? Do they perform the same function? Are they made of the same chemical compounds? 

Pregnenolone is, in fact, not the same as the DHEA hormone as they both perform different functions in the body, irrespective of the fact that both hormones are steroid hormones. We will take a look at the roles of both hormones in the body and see the difference between the two. 

The Role of DHEA in the Body 

DHEA is a derivative of pregnenolone. It is involved in the productions of estrogen in the body. DHEA is also involved with the development of strong bones in the body, which is why older people are advised to consume supplements containing DHEA to prevent the loss of bone thickness and osteoporosis. 

The Role of Pregnenolone in the Body 

Pregnenolone is first stored as cholesterol in the body and converted by various glands into an effective hormone. Pregnenolone is also known as a prohormone or a precursor hormone because it is responsible for the production of other vital hormones in the body, particularly sex hormones, stress hormones, and neuron hormones. This is what makes the pregnenolone hormone very important because an imbalance of other hormones can be traced back to an imbalance of the taking pregnenolone hormone, seeing that it is a building block for many other hormones in the body. 


The pregnenolone hormone is an important or one as it is either directly or indirectly responsible for many bodily functions, for example, the nervous response of fight or flight in PNS, which is controlled by the cortisone hormone. Still, the cortisone hormone is also a derivative of pregnenolone. Other important hormones that are created by pregnenolone include estrogen, progesterone, testosterone, and many others. Not only does this hormone create other hormones, but it also plays a role in resulting emotions, improve sleep and brain function, and even to maintain body weight. 


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